Friday, October 15, 2010

Relationship between psychotic and obsessive compulsive symptoms in schizophrenia

The presence of obsessive compulsive symptoms (OCSS) in schizophrenia was recognized in the earliest descriptions of the disease. Studies investigating the association between schizophrenia OCSS and have defined their co-occurrence in terms of co-morbidities and patients with schizophrenia compared separated into groups according to whether or not CSOs.

However, most of these studies were not both the complexity of the phenomenology of schizophrenia and the OCSS into account. This study investigates the relationship between symptoms of schizophrenia and CSOs using a correlation approach to a three-dimensional perspective to determine how the OCSS contribute to the expression of symptoms in schizophrenia. Fifty-nine patients with schizophrenia were classified for the symptoms of schizophrenia (SAPS-SANS) and CSOs (Y-BOCS). symptoms of schizophrenia results are regrouped in four dimensional scores and other results CSOs dimensions.

The latter were introduced as explanatory variables in partnerships with dimension scores in schizophrenia using a series of stepwise regression models.

The results showed a strong positive relationship between delusions and obsessions in line with the view that they reflect manifestations of similar mechanisms. Similar results showing an association between auditory hallucinations and compulsions also suggests that share common mechanisms.

On the other hand, there was an inverse relationship between somatic obsessions and disorganization and between Hoarding / Collecting compulsions and delusions or hallucinations.

These results may reflect that these CSOs have a protective effect against disorganization and psychotic symptoms, respectively.

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